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Índice >> Revista de Neurología (Volumen 53  Núm 6) >> Brachial arterial flow mediated dilation: utility ...

Brachial arterial flow mediated dilation: utility in clinical and experimental practice imprimir
Revisión Castellano   English
[REV NEUROL 2011;53:351-360] PMID: 21894606 - Revisión - Date of publication: 16/09/2011
D. Santos-García, M. Rodríguez-Yáñez, S. Arias-Rivas, M. Blanco
Brachial artery flow mediated dilation (FMD) is a validated, noninvasive physiological measure widely used as a research tool to quantify endothelial function. FMD is diminished in patients with several coronary risk factors, coronary artery disease, peripheral arterial disease, stroke, and is an independent predictor of cardiovascular events. FMD represents a useful method for identify asymptomatic atherosclerotic subjects with raised risk of developing atherothrombotic complications and improves with risk-reduction therapy such as antihypertensive or antidiabetic drugs, antiplatelet agents and statins. FMD could be a great usefulness in ischemic stroke such as stroke subtypes classification, prognostic significance in acute phase, and independent predictor for new-onset vascular event after first-ever stroke, but also in other disease such as cerebral haemorrhage, migraine or syncope. In this review article, brachial artery FMD and its role in experimental and clinical practice is extensively discussed.
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Santos-Garcia D
Rodriguez-Yañez M
Arias-Rivas S
Blanco M
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Brachial artery
Endothelial dysfunction
Endothelium
Flow mediated dilation
Ischemic stroke
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Keywords:  Brachial artery - Endothelial dysfunction - Endothelium - Flow mediated dilation - Ischemic stroke
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Classified in: Patología vascular
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